Posts

Showing posts from July, 2021

What Are Bile Acid Metabolites & How The Health Issue Is Treated?

Image
As the gut microbiota contributes to metabolic health, it is important to determine specific diet-microbiota interactions that influence the host of metabolism. Bile acid metabolites can alter phenotypes of diet-induced obesity. The bacterial bile acid metabolites, termed secondary bile acids, are more hydrophobic than primary bile acids produced by the liver. As the gut microbiota contributes to metabolic health, it is important to determine specific diet-microbiota interactions that influence host metabolism.   Bile acids and dietary fat sources can alter phenotypes of diet-induced obesity, but the interplay with intestinal microorganisms is unclear.  Bile contains bile acids that are crucial for the digestion and absorption of fats and fat-soluble vitamins in the small intestine. Waste products like bilirubin are eliminated from the body by secretion into bile and elimination in feces. The Role of Bile Acid in Fat Digestion and Absorption Bile acids are the byproducts of cholestero

What is HPLC (High-performance liquid chromatography) analysis?

Image
High-performance liquid-like chromatography is one of the most important and common quantitative and qualitative methods; however, the lack of some of these top tips for HPLC analysis in pharmaceuticals can be too complicated. Press the wrong elements of the analysis, for example, temperature. These tips include understanding HPLC analysis. In this case, it is about optimizing selectivity. What are the different tips related to HPLC (High-performance liquid chromatography) analysis? The following are the mentioned tips that are related to HPLC analysis: One is to avoid reinventing the wheel, which would lead to a lot of experimentation and thus a waste of time. Instead, the existing literature on what has been done before should be consulted to determine the appropriate conditions. The most suitable HPLC analysis defines and depicts normal phase HPLC or reversed-phase HPLC.    Another tip is to determine the required sample preparation. Sample preparations vary, among other things, fro